Ivermectin Sars Cov 2


I was sick of ignorant people saying Ivermectin has “insufficient evidence” it works. I prepare this response complete with all scientific references. Feel free to copy and paste to those people who still don’t know. Hope it helps.
Ivermectin is a 40 year old medicine. It’s discovery won its inventor’s the Noble Prize in medicine. Billions of doses has been given to humans safely. It is proven safe up to 10x the prescribed dose (1). It is widely used in veterinary medicine. It is a common overt-the-counter medicine in some countries used to treat parasite infections. When re-purposed to treat Covid 19, the scientific studies show that it works in the following ways (all references included below):
Video explanation of modes of operation from Dr Mobeen Syed:
https://www.youtube.com/watch?v=GZoBAuR4ajs
1. It hinders the binding of the SARS-COV-2 spike protein with the ACE2 receptor on our cells.
2. It disrupts the RdRp enzyme of the virus reducing the viruse’s replication.
3. It disrupts the 3-chymotrypsin like protease enzyme of the virus, resulting in the reduction in virus replication.
4. It disrupts the importin alpha and beta of our cells. These proteins are used by the virus to send messages to our nucleus not to defend itself. Ivermectin disrupts these messages resulting in better cellular defense by our tissues.
5. As a result of all of the above, it PREVENTS and TREATS Covid 19.
References for all statements above:
1. Safety, tolerability, and pharmacokinetics of escalating high doses of ivermectin in healthy adult subjects
https://pubmed.ncbi.nlm.nih.gov/12362927/
2. The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
https://www.sciencedirect.com/science/article/pii/S0166354220302011
3. Ivermectin is a specific inhibitor of importing α/β-mediated nuclear importable to inhibit replication of HIV-1 and dengue virus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327999/
4. Ivermectin as an anti-inflammatory
https://pubmed.ncbi.nlm.nih.gov/19453757/
5. Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2
https://iv.iiarjournals.org/content/34/5/3023
6. Ivermectin as a promising RNA-dependent RNA polymerase inhibitor and a therapeutic drug against SARS-CoV2: Evidence from in silico studies
https://www.researchsquare.com/article/rs-73308/v1
7. Ivermectin for Prevention and Treatment of COVID-19 Infection
https://journals.lww.com/americantherapeutics/Abstract/9000/Ivermectin_for_Prevention_and_Treatment_of.98040.aspx
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